Name: ReadiUse™ probenecid *25 mM stabilized aqueous solution*
Brand: AAT Bioquest
SKU: 20062
Price: 174 USD
Availability: InStock

ReadiUse™ probenecid

25 mM stabilized aqueous solution

Probenecid is an inhibitor of organic-anion transporters located in cell membranes. These transporters often extrude fluorescent indicators from cells, and therefore contribute to poor dye retention. This phenomenon usually causes high background in the assays that require the good retention of the dye indicators inside cells. The use of probenecid to inhibit the transporter activity, and thus to reduce leakage of the intracellular dye indicators is a common method for reducing fluorescence background of calcium assays. The commonly used free acid form of probenecid requires the use of 1 M NaOH to dissolve it due to its poor water solubility in neutral water. AAT Bioquest offer the convenient Readiuse™ water-soluble and heat-stable probenecid in the format of a powder, solution or tablet. They are convenient to use and are as effective as the free acid form at the same concentration. Each vial is diluted with 90 mL buffer to make 2.5 mM final concentration of probenecid for your assays.

Protocol

SDS

COA

Catalog	Size	Price	Quantity
20062	10x10 mL	Price

Citations

View all 13 citations: Citation Explorer

Optimization of Magnetoelectric Nanoparticles for Applications in Cancer Theranostics

Authors:

Shotbolt, Max

Translational selenium nanomedicine synergizes with nab-paclitaxel to enhance antitumor effects in esophageal squamous cell cancer via selenoprotein N-mediated ER stress

Authors:

Huang, Haoyang and Liu, Shaowei and Xu, Ligeng and Liang, Hengrui and Wu, Zihao and Chen, Tianfeng and Wang, Jinlin and Liu, Jun

Journal:

Journal of Nanobiotechnology (2025): 294

Mitochondrial-dependent oxidative phosphorylation is key for postnatal metabolic adaptation of alveolar macrophages in the lung

Authors:

Zhang, Jun and Peng, Yu and Song, Haosen and Liu, Siqi and Li, Chuanwei and Zhang, Yi and Shi, Xiaowei and Guo, Huifang and Xu, Yingping

Journal:

International Immunopharmacology (2024): 112012

Magnetic-field-synchronized wireless modulation of neural activity by magnetoelectric nanoparticles

Authors:

Zhang, E and Abdel-Mottaleb, M and Liang, P and Navarrete, B and Yildirim, Y Akin and Campos, M Alberteris and Smith, IT and Wang, P and Yildirim, B and Yang, L and others,

Journal:

Brain Stimulation (2022): 1451--1462

Pharmacogenomic screening of drug candidates using patient-specific hiPSC-derived cardiomyocyte high-throughput calcium imaging

Authors:

Blancard, Malorie and Fetterman, K Ashley and Burridge, Paul W

References

View all 35 references: Citation Explorer

DNA damage caused by benzo(a)pyrene in MCF-7 cells is increased by verapamil, probenecid and PSC833

Authors:

Myllynen P, Kurttila T, Vaskivuo L, Vahakangas K.

Journal:

Toxicol Lett (2007): 3

Is the monkey an appropriate animal model to examine drug-drug interactions involving renal clearance? Effect of probenecid on the renal elimination of H2 receptor antagonists

Authors:

Tahara H, Kusuhara H, Chida M, Fuse E, Sugiyama Y.

Journal:

J Pharmacol Exp Ther (2006): 1187

Inhibition of oat3-mediated renal uptake as a mechanism for drug-drug interaction between fexofenadine and probenecid

Authors:

Tahara H, Kusuhara H, Maeda K, Koepsell H, Fuse E, Sugiyama Y.

Journal:

Drug Metab Dispos (2006): 743

MRP2 (ABCC2) transports taxanes and confers paclitaxel resistance and both processes are stimulated by probenecid

Authors:

Huisman MT, Chhatta AA, van Tellingen O, Beijnen JH, Schinkel AH.

Journal:

Int J Cancer (2005): 824

Mediation of annexin 1 secretion by a probenecid-sensitive ABC-transporter in rat inflamed mucosa

Authors:

Wein S, Fauroux M, Laffitte J, de Nadai P, Guaini C, Pons F, Comera C.

Journal:

Biochem Pharmacol (2004): 1195

Physical properties

Molecular weight	307.34
Solvent	Water

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C); Minimize light exposure
UNSPSC	12352200

Telephone
Fax
Email	sales@aatbio.com
International	See distributors
Bulk request	Inquire
Custom size	Inquire
Technical Support	Contact us
Request quotation	Request
Purchase order	Send to sales@aatbio.com
Shipping	Standard overnight for United States, inquire for international

Page updated on October 8, 2025