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TRITC Anti-human CD14 Antibody
61D3
61D3 is an anti-human monoclonal antibody that targets the CD14 antigen. CD14 (sometimes referred to as myeloid cell-specific leucine-rich glycoprotein or LPS receptor) is a transmembrane protein that is located on the surface of cells such as macrophages. CD14 acts in critical cellular pathways, for example, the toll-like receptor signaling pathway, cell surface receptor signaling pathway and lipopolysaccharide-mediated signaling pathway. Moreover, in certain organisms, it promotes interleukin-8 secretion, is a positive regulator of tumor necrosis factor production and is a promoter of type I interferon production. From a research standpoint, it is of biological interest due to its association with essential macromolecules/ligands like LY96. CD14 is a very popular antibody target, with over 42000 publications in the last decade. CD14 is essential for immunology, cell biology and neuroscience research, often serving as a phenotypic marker for differentiating cell types in flow cytometric applications. This antibody was purified through affinity chromatography and conjugated to TRITC (ex/em = 544/570 nm). It is compatible with the 561 nm laser and 582/15 nm bandpass filter (for example, as in the BD FACSAria™ III).
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CatalogSize
Price
Quantity
101411I0100 tests
Price
101411I1500 tests
Price
 
Antibody properties

Other namesLPS-Receptor
Clone61D3
Hostmouse
Reactivityhuman
ApplicationFlow Cytometry (FACS); Fluorescence Imaging
Spectral properties

Correction factor (260 nm)0.27
Correction factor (280 nm)0.34
Extinction coefficient (cm -1 M -1)
100000
Excitation (nm)544
Emission (nm)570
Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
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Page updated on October 29, 2025