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AAT Bioquest

Is SDS considered a detergent?

Posted July 30, 2021


Answer

Yes, SDS is considered a detergent. SDS stands for Sodium Dodecyl Sulfate. It is an anionic detergent capable of disrupting non-covalent bonds within and between proteins, denaturing them, and resulting in the loss of their native structure and function. It is effective in both alkaline and acidic solutions and is often used in protein and lipid solubilization.

Additional resources

Specific Ion Effects of Dodecyl Sulfate Surfactants with Alkali Ions at the Air–Water Interface