AAT Bioquest

What are cellular spheroids?

Posted January 7, 2022


Cellular spheroids are multicellular cell aggregates that form via Extracellular Matrix (ECM) fibers that link single cells together. Cellular spheroids are more complex than single cells. The dynamic cell-to-cell and cell-to-matrix interactions create an environment that closely and realistically resembles the environmental conditions of live cells. This makes them a vital tool for studying in vivo microenvironment of tissues in vitro.

Additional resources

Cell spheroids: the new frontiers in in vitro models for cancer drug validation

Cell Meter™ Fixed Cell and Tissue TUNEL Apoptosis Assay Kit *Deep Red Fluorescence*