AAT Bioquest

What are the applications of NGS?

Posted February 16, 2022


NGS (next generation sequencing) has made it possible for researchers to gather vast amounts of genomic sequencing data, which has a broad range of applications. NGS enables labs to:

  • Rapidly sequence whole genomes
  • Discover novel RNA variants
  • Deeply sequence target regions
  • Sequence cancer samples
  • Analyze epigenetic modifications
  • Sequence exomes
  • Study the human microbiome
  • Identify and isolate genes responsible for certain diseases
  • Understand how organisms are affected by altered expression of genetic variants
  • Uncover mutations and pathways associated with rare genetic diseases
  • Provide the correct copy of a defective gene for gene therapy
  • Explore the tumor microenvironment and study gene expression patterns to better understand drug resistance and metastasis
Additional resources

Next-generation sequencing and its clinical application