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AAT Bioquest

What are the similarities between linear and circular DNA?

Posted March 24, 2022


Answer

Linear and circular DNA are two different types of DNA structures. Similarities between linear and circular DNA include:

  • Both have a double-stranded helical structure
  • Both are compared of Deoxyribose nucleic acids containing adenine, cytosine, guanine, and thymine nucleotides
  • Both store genetic information and determine the genetic characteristics of organisms
  • Plasmids can occur in both
  • Both forms can be amplified using techniques such as PCR (Polymerase Chain Reaction)
  • Both can be separated using agarose gel electrophoresis methods
  • Both can be used in DNA-based diagnostics and in genetic engineering applications
Additional resources

Supercoiled and linear plasmid DNAs interactions with methylene blue

Gelite™ Safe DNA Gel Stain *10,000X Water Solution*