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What is the difference between miRNA and mRNA?
Posted February 3, 2021

Answer

miRNA stands for micro RNA and mRNA stands for messenger RNA. Here’s a look at the differences between the two.

miRNA

  • Is only present in eukaryotic cells but absent in prokaryotic cells
  • Functions as an epigenetic repressor of protein translation
  • Is a short nucleotide sequence measuring approximately 20-22 nt
  • Is smaller than most forms of RNA
  • Capable of controlling gene expression
  • Is believed to have evolved from CRISPR genes of bacteria

mRNA

  • Is present in both eukaryotic and prokaryotic cells
  • Functions as a messenger, carrying messages from DNA in the nucleus to ribosomes on the ER, where it is first translated into a corresponding sequence of amino acids and then synthesized into protein
  • Is directly transcribed from DNA
  • Capable of detecting the amino acid sequence of a peptide
  • Evolves on mutation of its parent gene