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AAT Bioquest

What is the difference between reactogenicity and the immunogenicity of a vaccine?

Posted April 24, 2020


Answer

Immunogenicity is the ability of a vaccine to elicit an immune response against a pathogen, while reactogenicity is the degree to which a vaccine can produce excessive immune response and adverse reactions, such as fever or swelling. Ideally, vaccines should induce a sufficient immune response without being too reactogenic.