logo
AAT Bioquest

What is the molecular weight (mw) of alcohol dehydrogenase (ADH)?

Posted June 1, 2018


Answer

82 kDa

 

Alcohol dehydrogenases (ADH) oxidises alcohol into aldehydes orketones. The enzyme occurs in various mammalian tissues but is found in relatively high concentrations in liver and kidney. Alcohol dehydrogenase from equine liver is a homodimer with a molecular weight of 82,000 daltons, which is equivalent of 82,000 g/mol. Each monomer contains 374 amino acids and has a mass of 41 kDa.

Additional resources

Examination of the Dissociation of Multichain Proteins in Guanidine Hydrochloride by Membrane Osmometry

Structure of horse liver alcohol dehydrogenase: I. Structural symmetry and conformational changes