AAT Bioquest

What is the molecular weight (mw) of aldolase?

Posted June 21, 2018


160 kDa


Aldolase is present in all animal and plant tissue, and in most microorganisms. Class I aldolase is found in animal and higher plant tissue, while Class II aldolase is found only in prokaryotes and lower eukaryotes. There are three types of Class I aldolases: Type A (the major form) is found in muscle; Type B in liver and kidney; and Type C (plus some A) in brain. The molecular weight of aldolase is 160 kDa, which is equivalent of 160,000 g/mol. It exists as a homotetramer of four equal subunits of molecular weight 40 kDa.

Additional resources

Examination of the Dissociation of Multichain Proteins in Guanidine Hydrochloride by Membrane Osmometry