What is the working mechanism of Ionomycin?
Posted June 26, 2019
Ionomycin is a calcium ionophore used to increase intracellular calcium concentration, it does so by:
- Facilitating the transport of Ca2+ across the plasma membrane.
- Releasing Ca2+ from its intracellular stores without the involvement of G proteins, resulting in the activation of calcium-activated chlorine channels.
- Acts on the same intracellular Ca2+ stores as 'P3