logo
Products
Technologies
Applications
Services
Resources
Selection Guides
About
Are there any red calcium flux dyes?
Posted February 2, 2024

Answer

Yes, there are several red calcium flux dyes. One example is BioTracker NIR Ca2+ dyes, including SCT021, SCT022, and SCT023. These are fluorescent calcium indicators that emit light in the far-red spectrum. These dyes exhibit a substantial change in fluorescence intensity (up to a 1000-fold increase) upon binding to calcium ions within viable cells. The red calcium dye, ION Calcium Red-1 (ICR-1), is a fluorescent indicator which emits light in the red spectrum (Ex/Em: 580/660 nm) in response to changes in intracellular calcium levels. Its unique spectral properties enable the simultaneous use of another indicator of a different color or the observation of cells expressing GFP tags. Another example is Fura Red, which is a fluorescent dye that is sensitive to changes in calcium concentration. Its fluorescence decreases as the concentration of calcium ions increases. When Fura Red binds to calcium, it becomes a fluorescent compound that can be excited at 435 nm, emitting light at a peak wavelength of 639 nm.