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Do lyases and ligases require external energy sources for their catalytic activities?
Posted March 26, 2024
Antibodies and Proteomics BioconjugationCellular ProcessesCellular Structures and OrganellesEnzymesPhysiological Probes
Answer

Only ligases require external energy sources for their catalytic activities. The energy required to drive the formation of covalent bonds is typically derived from hydrolysis of ATP. 

Lyases do not require any external energy source for their catalytic activities. 

Additional resources
Exploring the Biological and Chemical Complexity of the LigasesEnzymesPeptide and Protein Molecular Weight Calculator

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