Do neurons have the Major Histocompatibility Complex (MHC)? | AAT Bioquest

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Do neurons have the Major Histocompatibility Complex (MHC)?

Posted August 26, 2024

Antibodies and Proteomics Bioconjugation Chemical Reagents Cell Signaling Cellular Processes Immunohistochemistry (IHC)Physiological Probes

Answer

No, neurons do not have the Major Histocompatibility Complex (MHC).

Major Histocompatibility Complex is a cell cluster that is found on the surface of nucleated cells. Neurons, which are cells of the nervous system, are anucleated, and as such they do not have the MHC.

Additional resources

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