logo
Products
Technologies
Applications
Services
Resources
Selection Guides
About
How do I quantify the basicity of amines?
Posted May 17, 2024
Chemical ReagentsIntracellular IonsIntracellular pH
Answer

To quantify the basicity of amines, one should look at the pKa of its conjugate acid. The higher the pKa of the conjugate acid, the stronger the base. In contrast, the lower the pKa of the conjugate acid, the weaker the base.

Additional resources
Basicity of AminesIntracellular pH Weak Base pH Calculator

How do I use pKa values to tell if an acid base reaction is favorable or unfavorable?What are the components of an acid-base reaction?What are the important factors that affect the basicity of amines?How do acid-base reactions affect the reactivity of a molecule?What is the chemical reaction between an acid and a base?