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How do I quantify the basicity of amines?
Posted May 17, 2024
Chemical ReagentsIntracellular IonsIntracellular pH
Answer
To quantify the basicity of amines, one should look at the pKa of its conjugate acid. The higher the pKa of the conjugate acid, the stronger the base. In contrast, the lower the pKa of the conjugate acid, the weaker the base.
Additional resources
Basicity of AminesIntracellular pH Weak Base pH Calculator

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