AAT Bioquest

How does alternative splicing work?

Posted October 22, 2022


Alternative splicing is a type of post-transcriptional modification. Specific chemical factors stimulate the spliceosome to function in different ways. Through signals, exons or fragments of exons within a single stranded pre-mRNA are either rearranged or skipped, resulting in a variety of protein isoforms being encoded from a single gene. 

Additional resources

Mechanism of alternative splicing and its regulation

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