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How is the basement membrane formed?
Posted October 27, 2023

Answer

The basement membrane is formed from a self-assembly process by a mixture of molecules including IV collagen and laminin. Laminins and type IV collagens are bound to nidogens -1 and -2 and to the proteoglycans agrin and perlecan. Integrins and dystroglycan are two types of receptors which facilitate the formation of the network of laminin.