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How will the isoelectric points be affected by acidic side chains?
Posted May 17, 2024
Chemical Reagents ToolsIntracellular IonsIntracellular pH
Answer
Amino acids with acidic side chains tend to have lower isoelectric points because they readily accept protons. In contrast, those with basic side chains typically have higher isoelectric points because they readily donate protons.  
Additional resources
Amino Acids, the Henderson-Hasselbalch Equation, and Isoelectric PointsIsoelectric Point Calculator Henderson-Hasselbalch Acid Calculator

What factors determine the strengths of acids and bases?How do I calculate isoelectric points?How do I calculate pH from pKa and concentration?What is basicity of amines?How do I use pKa values to tell if an acid base reaction is favorable or unfavorable?