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AAT Bioquest

Is CD45 a cell surface marker?

Posted July 8, 2022


Answer

Yes, CD45 is a cell surface marker. It marks the surface of nucleated hematopoietic cells involved in activating and regulating the immune system and is of great value in differentiating between lymphoproliferative disease subtypes.

Additional resources

Diagnostic and prognostic significance of CD45 cell surface antigen expression in hematologic malignancies with main focus on acute leukemias

mFluor™ UV375 Anti-human CD45 Antibody *HI30*

CD45 (Protein tyrosine phosphatase, PTPRC)