AAT Bioquest

Where is CD45 found?

Posted July 8, 2022


CD45 is found on the surface of all nucleated hematopoietic cells with the exception of platelets and red blood cells. CD45 is a type I transmembrane molecule and a key regulator of antigen-mediated signaling and activation in T and B cells. It comprises up to 10% of the cell surface area in T and B cells. 

Additional resources

Calcein UltraBlue™ AM

mFluor™ UV375 Anti-human CD45 Antibody *HI30*

CD45 and the immune response