What are differences between antibody affinity and avidity?
Posted October 10, 2023
Answer
Basis of differentiation |
Antibody affinity |
Antibody avidity |
Definition |
The attraction which a specific antibody binds to its corresponding antigen |
Is the strength which an antigen-antibody immune complex possesses at that epitope |
Strength |
Is comparatively low |
Is comparatively high |
Mechanism |
The strength is generated by a single epitope interaction with a paratrope on the antibody |
The strength is produced by several avidities |
Antibody type |
Antibodies are monovalent or divalent |
Antibodies are multivalent |
Specificity |
Antibodies require a high specificity towards its epitopes |
Antibodies have less specificity towards their antigens |
Additional resources
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