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AAT Bioquest

What are the applications of hydrolases?

Posted January 22, 2024


Answer

Hydrolases are a diverse class of enzymes that catalyze hydrolysis reactions, in which a substrate is cleaved by the addition of water molecules. These enzymes play crucial roles in various biological and industrial processes. 

Key applications of hydrolases include but are not limited to: 

  • Digestion in living organisms: Hydrolases facilitate digestion by breaking down large complex molecules such as carbohydrates, proteins, and lipids into simpler forms that the body can easily absorb and utilize.  
  • Pharmaceutical industry: Hydrolases such as esterases and glycosidases are used extensively in pharmaceutical manufacturing to synthesize certain drugs and drug intermediates. 
  • Food industry: The food industry uses hydrolases for various purposes such as improving flavor profiles, modifying starches, and clarifying fruit juices. Hydrolases such as amylases and cellulases are used in food processing. 
  • Detergent industry: Hydrolases such as lipases and proteases are used extensively in the detergent industry. These enzymes enhance the cleaning properties of laundry detergents by breaking down protein and lipid stains on fabrics. 
  • Wastewater treatment industry: Hydrolases help in treating wastewater by breaking down organic compounds. For example, lipases hydrolyze fats and oils, facilitating their degradation during the wastewater treatment process. 
Additional resources

The Cell: A Molecular Approach. 2nd edition.

Enzymes

Amplite® Fluorimetric Coenzyme A Quantitation Kit *Green Fluorescence*