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What are the common amine-reactive moieties?
Posted May 23, 2024
Antibodies and Proteomics BioconjugationAntibody and Protein LabelingDyes by Functional Group
Answer
Common amine-reactive moieties include isothiocyanates, epoxides, succinimidyl esters, acyl azides, anhydrides, and NHS esters. These moieties typically react with amines through either alkylation or acylation processes.
Additional resources
Amine-Reactive Activated Esters of meso-CarboxyBODIPY: Fluorogenic Assays and Labeling of Amines, Amino Acids, and ProteinsAmine Reactive Dyes and Probes for Conjugation iFluor® 488 succinimidyl ester

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