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AAT Bioquest

What are the differences between dissociation and solvation?

Posted March 17, 2023


Answer

Dissociation and solvation are terms that describe how substances break down or split into small pieces or atoms/ions depending on the interactions. There are a few significant differences between these two processes. 

Dissociation

  • Dissociation refers to the breakdown of a compound into smaller particles. The smaller particles may be atoms or ions which make up the compound.
  • It involves the breakdown of a large substance into smaller pieces.
  • External factors such as intermolecular interactions, heat, and dissolution cause the molecules, atoms, or ions of a substance to separate from each other
  • Example: Chemical bonds of maltose are broken down by maltase enzymes resulting in glucose units, which make up maltose  

Solvation: 

  • Solvation refers to the dissolution of a substance in a particular solvent due to the attraction forces between the components of the substance and the solvent molecules.
  • It involves the dissolution of a substance in a solvent.
  • Attraction forces between molecules or ions of a substance cause the molecules or ions of a substance to separate from each other. 
  • Example: Sodium chloride ionic compound breaks down when it is dissolved in water.
Additional resources

Biochemistry, Dissolution and Solubility

Solubility Reference Table

Serial Dilution Calculator and Planner