The terms lipophilic and hydrophilic describe the solubility of a compound. There are several differences between these two terms. 

Lipophilic 

• Refers to the ability of a substance to dissolve in lipids or fats
• Soluble only in lipophilic solvents such as lipid, oil, fat and nonpolar solvents such as hexane, etc. 
• Chemical composition is mostly organic, nonpolar portions of molecules
• Examples include fat-soluble vitamins, amino acids, hormones, and hydrocarbon compounds among others

Hydrophilic

• Refers to the ability of a substance to dissolve in water or other hydrophilic solvents
• Soluble only in hydrophilic solvents such as water
• Contains polar functional groups
• Examples include sugars, salts, alcohols, and soap