Forward primer and reverse primer are two types of primers used in the process of PCR (polymerase chain reaction). There are a few notable differences between the two. 

• Forward primers are DNA segments that are complementary to the antisense strand of double-stranded DNA. 
• They are also known as 5′ primers because they occur at the 5′ end of the PCR product. 
• Forward primers bind to the antisense strand (-) of the DNA that runs in 3′ to 5′ direction. They are responsible for the amplification of the antisense strand.
• Forward primers anneal with the template strand to facilitate the synthesis of the coding sequence.

• Reverse primers are DNA segments that are complementary to the sense strand of the double-stranded DNA.
• They are also known as 3′ primers because they occur at the 3′ end of the PCR product. 
• Reverse primers bind to the sense strand (+) of the DNA that runs in the 5′ to 3′ direction. They are responsible for the amplification of the sense strand. 
• Reverse primers anneal with the non-template strand to facilitate the synthesis of noncoding sequences