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AAT Bioquest

What are the differences between LD50 and LC50?

Posted March 26, 2024


Answer

Key differences between LD50 and LC50:

LD50:

  • Stands for Lethal Dose 50%
  • Indicates the lethal dose of a substance that can cause 50% deaths when exposed to a population 
  • Unit of measurement is milligrams of substance per kilogram of population or mg/kg bw/d (mg of substance per kg of body weight administered per day

LC50:

  • Stands for Lethal Concentration 50%
  • Indicates the lethal concentration of a substance that can cause 50% deaths when exposed to a population
  • Unit of measurement is milligrams per cubic meter or ppm 
Additional resources

Comparing LD50/LC50 Machine Learning Models for Multiple Species

LD50 Calculator

LC50 Calculator