What are the differences between paracrine signaling and endocrine signaling?

Question

Accepted Answer

Basis of differentiation

Paracrine signaling

Endocrine signaling

Definition

Paracrine signaling is when a cell signals to its adjacent cells using chemical messengers

Endocrine signals transmit over long distances, typically using the circulatory system

Ligand concentration

Is comparatively low

Is comparatively high

Timespan

Are slow responses but induce long-lasting effects

Are fast responses but for shorter periods of time

Involvement of hormones

Hormones act locally via diffusion from their source to neighboring target cells

Hormones are dispersed in the blood and attach to distant target cells elsewhere in the body

Basis of differentiation	Paracrine signaling	Endocrine signaling
Definition	Paracrine signaling is when a cell signals to its adjacent cells using chemical messengers	Endocrine signals transmit over long distances, typically using the circulatory system
Ligand concentration	Is comparatively low	Is comparatively high
Timespan	Are slow responses but induce long-lasting effects	Are fast responses but for shorter periods of time
Involvement of hormones	Hormones act locally via diffusion from their source to neighboring target cells	Hormones are dispersed in the blood and attach to distant target cells elsewhere in the body