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AAT Bioquest

What are the differences between T memory cells and B memory cells?

Posted November 29, 2023


Answer

Basis of differentiation 

T memory cells

B memory cells

Definition 

Are generated by naïve T cells after successfully eliminating an antigen 

Are generated by naïve B cells after successfully eliminating an antigen

Origin 

Generate from effector T cells

Generate in response to T-dependent antigens

Occurrence 

In the mucosal tissue sites such as the lungs, skin, guts, and genital surfaces

In the bloodstream

Reaction on recognizing a returning pathogen

Quickly convert to effector T cells 

Mount a specific antibody response

Function 

React to the antigen-bearing pathogens in the mucosal tissue sites

Produce antibodies against the antigen

Additional resources

Memory B and T cells

CD3 (Leu4, T3)

iFluor® 488 Anti-human CD3 Antibody *HIT3a*