What are the effects of oxidative stress on the body?

Oxidative stress can induce and trigger inflammation. ROS can activate signaling pathways that induce the generation of proinflammatory molecules. Chronic inflammation associated with oxidative stress is involved in several diseases including cardiovascular diseases, autoimmune disease, and neurodegenerative diseases. Oxidative stress is also considered as one of the major factors in the aging process. Accumulated oxidative damage to cellular components over time can lead to reduced cellular lifespan and overall functional decline.