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AAT Bioquest

What are the functions of exosomes?

Posted July 21, 2023


Answer

Functions of exosomes in the body include:

Intercellular communication - The main function of exosomes is to facilitate intercellular signaling. Exosomes act as messengers between cells, allowing them to communicate and exchange information. They carry various molecules such as proteins, RNA, and lipids from one cell to another. By transferring these molecules, exosomes can influence the behavior, function, and signaling pathways of the recipient cells.

Immune response - Exosomes are also involved in immune responses by carrying molecules that stimulate or suppress immune responses, depending on the specific situation. For example, exosomes derived from immune cells can transfer signaling molecules to other immune cells, influencing their activity and coordinating immune reactions.

Tissue repair and regeneration – Exosomes have regenerative properties and contribute to tissue repair processes by stimulating cell growth, reducing inflammation, and promoting tissue healing and regeneration.

Disease modulation - Exosomes can play a role in various diseases, including cancer, by promoting tumor growth and influencing the spread of tumor cells.

Additional resources

Isolation and characterization of exosomes from cell culture supernatants and biological fluids

DiOC16(3) perchlorate [3,3-Dihexadecyloxacarbocyanine perchlorate]

DiR iodide [1,1-dioctadecyl-3,3,3,3-tetramethylindotricarbocyanine iodide]