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What are the main components of connective tissues?
Posted December 22, 2023
Answer
The main components of connective tissue include extracellular fibers, stationary and migratory cells, and ground substance (amorphous matrix).
- There are 3 types of extracellular fibers: collagenous, reticular, and elastic.
- The most predominant are the fibers which make up collagen (collagenous fibers). They are colorless strands with different diameters, and can function in any direction.
- Elastic fibers are composed of elastin and have different attributes than collagenous fibers. They do not possess the uniform subunits like collagenous fibers do.
- Reticular fibers are identified by their ability to create intricate networks surrounding cells and clusters of cells. They stand out due to their characteristic of appearing black when stained.
- Theground substanceis a clear substance which behaves like a thick liquid or very hydrated gel. It mainly comprises large molecules called glycosaminoglycans, which are a combination of proteins and carbohydrates.
- Stationary cellssuch as fibroblasts are the primary working cells found throughout connective tissue. They appear as elongated, spindle-shaped cells positioned along bundles of collagen fibers. Their main roles involve forming tropocollagen and other components of the tissues ECM.
- Mast cells are examples of migratory cells and are found in loose connective tissue. These cells contain large granules filled with histamine and heparin.