What are the pros of ultracentrifugation for exosome isolation?

Ultracentrifugation for exome isolation involves subjecting a sample to high centrifugal forces to separate exosomes from other cellular components based on their size and density.

Pros of ultracentrifugation: 

• Ultracentrifugation is considered one of the most effective methods for separating exosomes from other particles and protein aggregates present in biological fluids, resulting in a purer exosome sample that can be used for clinical studies   
• The procedure can be scaled up to process larger volumes of biological fluid, making it suitable for isolating exosomes from both small-scale experiments and larger clinical studies