What causes T cells to become exhausted? | AAT Bioquest

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What causes T cells to become exhausted?

Posted November 16, 2023

Antibodies and Proteomics Bioconjugation Antibody and Protein Labeling Cellular Processes Immunohistochemistry (IHC)Physiological Probes

Answer

T cell exhaustion is a term used to describe loss of functionality in T cells as a result of overstimulation. Exhausted T cells have not given up the fight against pathogens. They just exhibit weakened effector abilities and change tactics to defend the body in a different way.

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