What do mitochondrial fission and fusion mean? | AAT Bioquest

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What do mitochondrial fission and fusion mean?

Posted June 6, 2024

Cell Signaling Cellular Processes Cellular Structures and Organelles Mitochondria Physiological Probes

Answer

Mitochondrial fusion refers to the merging of two mitochondria into a single organelle. The process is primarily regulated by mitofusins. In contrast, mitochondrial fission involves the division of a single mitochondrion into two separate organelles. The two proteins which facilitate this process are Fis1 and Drp1.

Additional resources

Mitochondrial Fusion and Fission: The fine-tune balance for cellular homeostasis Mitochondria MitoLite™ Green FM

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