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AAT Bioquest

What is necrosis?

Posted April 10, 2024


Answer

Necrosis refers to the process of premature or unnatural cell death that is not internally regulated by cells. It is triggered by injury or disease and can occur at any point in the life cycle. 

Two examples of necrosis include:

  • Frostbite, which is caused by extreme cold conditions that trigger the necrosis of the body’s extremities such as the nose, fingers, and toes
  • Gangrene of the limbs, which is caused due to higher risk of injury and infection in individuals with diabetes
Additional resources

Many stimuli pull the necrotic trigger, an overview

Apoptosis and Necrosis

Cell Meter™ Apoptotic and Necrotic Multiplexing Detection Kit I *Triple Fluorescence Colors*