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AAT Bioquest

What is the composition of the cell envelope?

Posted March 2, 2023


Answer

The bacterial cell envelope provides the cell with structural integrity. There are two types of bacterial cell envelopes: Gram-positive cell envelope and Gram-negative cell envelope. 

Gram-Positive Cell Envelope

The cell envelope of gram-positive bacteria is made up of a thick cell wall, cytoplasmic membrane, and capsule. The cell wall is composed of a thick peptidoglycan layer that is embedded with teichoic acids and lipoteichoic acids.

Gram-negative Cell Envelope

The cell envelope of gram-negative bacteria is made up of a thin cell wall, cytoplasmic membrane, outer membrane, periplasmic space, and capsule. The cell wall is composed of a thin peptidoglycan layer. The outermost layer is made up of lipopolysaccharides and phospholipids.

Mycobacteria Cell Envelope

Mycobacteria have a cell wall that is different from that of both gram-positive and gram-negative bacteria. The outer cell membrane is absent in mycobacteria but there is a cell wall that is composed of peptidoglycan, mycolic acid, and arabinogalactan.

Additional resources

The Bacterial Cell Envelope

Gram Staining

MycoLight™ Rapid Fluorescence Gram-Positive Bacteria Staining Kit