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AAT Bioquest

What is the mechanism of oxidoreductase activity?

Posted January 16, 2024


Answer

Oxidoreductase enzymes facilitate electron transfers in various ways, such as transferring a hydride and a proton, two electrons and two protons, or a hydrogen atom, an electron, and a proton. Proteins alone aren't typically efficient in catalyzing these reactions. Instead, coenzymes and cofactors play a crucial role in providing the necessary chemical reactions for oxidoreductase catalysis. Many of these enzymes specifically catalyze reactions where an alcoholic group is dehydrogenated to form an aldehyde or ketone, concurrently reducing NAD+ to NADH.

Additional resources

Extremophilic Oxidoreductases for the Industry: Five Successful Examples With Promising Projections

Enzymes

Amplite® Fluorimetric Coenzyme A Quantitation Kit *Green Fluorescence*