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AAT Bioquest

What's the mechanism of immunological memory?

Posted February 28, 2024


Answer

Immunological memory refers to the immune system's capacity to react faster and more efficiently to pathogens it has faced before. Immunological memory relies on a process called clonal selection. When the immune system encounters an antigen, B cells identify it using specialized antibodies on their surface. This triggers a rapid expansion of activated B cells, generating both plasma cells that produce antibodies for immediate defense and memory B cells that retain the ability to recognize the antigen for future encounters. If the same pathogen is encountered again, the immune system triggers a stronger and quicker response, aiding in efficient pathogen clearance and preventing disease development or severe illness. Memory cells, with their extended lifespan, persist within the body over time.

Additional resources

Immunological Memory

Immunohistochemistry (IHC)

iFluor® 488 PSA™ Imaging Kit with Goat Anti-Mouse IgG