AAT Bioquest

What triggers necrosis?

Posted June 9, 2023


Necrosis can be triggered by several external factors and conditions. One factor is physical trauma, such as injuries from accidents or blunt force. Necrosis can also be triggered by toxins and chemicals such as illicit drugs, industrial chemicals, and environmental pollutants. Infections may also trigger necrosis, such as those caused by viruses which induce strong inflammatory responses. High levels of ionizing radiation, such as during radiation therapy for cancer treatments may result in unspecific and widespread necrosis in exposed tissues. Hypoxia and ischemia are also common causes of necrosis, and they can occur due to health conditions like arterial blockages, embolism, or thrombosis.

Additional resources

Cell Liquefactive Necrosis

Apoptosis and Necrosis

Multiplex Apoptosis and Necrosis

Cell Meter™ Apoptotic and Necrotic Multiplexing Detection Kit I *Triple Fluorescence Colors*