AAT Bioquest

When do chromosomes duplicate during a cell life cycle?

Posted June 1, 2022


Chromosomes duplicate during the S phase of interphase. This is part of the cell life cycle in which the cell is not actually dividing. In other words, the interphase is not part of mitosis. The S phase is a critical point during interphase during which the cell duplicates its chromosomes, resulting in two identical copies of each DNA. Each chromosome replicates to make a paired chromatid. At this stage, the cell contains double its normal number of chromosomes and is ready to move into the first phase of mitosis or cell division. 

Additional resources

Working on Genomic Stability: From the S-Phase to Mitosis

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