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Where are the G protein-coupled receptors (GPCRs) located?
Posted October 24, 2022
Answer
G protein-coupled receptors (GPCRs) are located in the cell membrane of eukaryotic organisms including animals, plants, yeast and choanoflagellates. Each GPCR is made up of a single polypeptide that’s folded into a globular shape. It lies embedded in the plasma membrane of the cell. 7 segments of a GPCR molecule cover the entire width of the membrane with the intervening portions looping inside and outside the cell.
Additional resources
The structure and function of G-protein-coupled receptors
Cell Navigator® Cell Plasma Membrane Staining Kit *Green Fluorescence*
Cell Navigator® Mitochondrion Staining Kit *Blue Fluorescence*