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AAT Bioquest

Why is the electron transport chain crucial in energy synthesis?

Posted February 8, 2024


Answer

The electron transport chain is crucial in energy synthesis because of the key role it plays in the production of ATP (adenosine triphosphate), which serves as the primary energy currency of cells. 

The electron transport chain (ETC) is a series of four protein complexes bound to the inner mitochondrial membrane. It is responsible for generating a proton gradient across the inner mitochondrial membrane in the final stage of cellular respiration. This proton gradient is created as electrons are transferred through the series of protein complexes in the ETC. The proton gradient created by the electron transport chain represents stored energy. ATP synthase, an enzyme complex embedded in the inner mitochondrial membrane, harnesses the energy stored in the proton gradient to synthesize energy in the form of ATP. 

Faulty electron transport chains can result in depleted energy levels and the creation of reactive oxygen species that can negatively impact the health and functioning of cells. 

Additional resources

Optimizing the electron transport chain to sustainably improve photosynthesis

Cell Signaling

PhosphoWorks™ Fluorimetric ATP Assay Kit