ED50 (or "median effective dose") represents the dose at which a substance produces a therapeutic or desired effect in half of the members of a tested population. The therapeutic effect is a binary measurement, meaning either the desired effect occurs or it does not. In pharmacology, the ED50 value is important because it serves as a rough guideline for the efficacy of a drug. It differs from the EC50 of a substance, though the two sound similar. Namely, the EC50 represents the dose at which a substance produces half of its maximal effect whereas the ED50 represents the dose at which a substance produces an effect in half of the population.
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MLA | "Quest Graph™ ED50 Calculator." AAT Bioquest, Inc., 30 Sep. 2025, https://www.aatbio.com/tools/ed50-calculator. | |
APA | AAT Bioquest, Inc. (2025, September 30). Quest Graph™ ED50 Calculator. AAT Bioquest. https://www.aatbio.com/tools/ed50-calculator. | |
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