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Psoralen is a compound derived from plants, naturally occurring as an insecticide, which becomes active when exposed to light. It increases the skin's sensitivity to longwave ultraviolet radiation, making it effective in UV light therapy. In this therapy, psoralen is absorbed into the epidermal cells where it interacts with human DNA under UV light. Psoralen has been utilized to treat skin conditions such as vitiligo, psoriasis, and specific types of skin nodules associated with cutaneous T-cell lymphoma. This compound is found in various plants including figs, celery, parsley, parsnip, clove, and citrus fruits, and can be administered topically or orally for medicinal purposes.
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Units/ml =
(∆A550/min x DF x 0.2)(Sample Vol x 21.1)
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