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ReadiLink™ Psoralen-A17-Biotin
ReadiLink™ Psoralen-A17-Biotin is a photoactivatable reagent for biotinylating DNA or RNA. It has the 4,5’8-trimethyl psoralen (TMP) group that can intercalate into double-stranded DNA or RNA and form covalent bonds with thymine and other pyrimidine bases when exposed to UV light (around 350 nm). Psoralen-PEG3-Biotin contains a polyethylene glycol (PEG) spacer arm (~45 Armstrong) that enhances the solubility and accessibility of the biotin moiety. Psoralen-A17-Biotin can be used for selective labeling of cell surface proteins, tissues and other biological samples. It can also be used to study the interactions between nucleic acids and proteins. Compared to the psoralen-PEG3-biotin, Psoralen-A17-Biotin is much more effective under the same conditions. It is a superior replacement for psoralen-PEG3-biotin.
Gel electrophoresis was performed on DNA (1 Kb Plus ladder) labeled with ReadiLink™ Psoralen-A17-Biotin (Cat# 3052) or a comparable product from Competitor A. The biotin-labeled DNA was incubated with Streptavidin (SA) for 30 minutes before loading onto the gel. The gel was then stained using Gelite Safe DNA gel stain (Cat# 17704), and the image was captured using a gel imager with a SYBR filter.
Gel electrophoresis was performed on DNA (1 Kb Plus ladder) labeled with ReadiLink™ Psoralen-A17-Biotin (Cat# 3052) or a comparable product from Competitor A. The biotin-labeled DNA was incubated with Streptavidin (SA) for 30 minutes before loading onto the gel. The gel was then stained using Gelite Safe DNA gel stain (Cat# 17704), and the image was captured using a gel imager with a SYBR filter.
CatalogSize
Price
Quantity
390521 mg
Price
390535 mg
Price
 
Physical properties

Molecular weight739.89
SolventDMSO
Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
StorageFreeze (< -15 °C)
UNSPSC12171501
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Page updated on October 15, 2025