ReadiLink™ Psoralen-A17-Biotin

ReadiLink™ Psoralen-A17-Biotin is a photoactivatable reagent for biotinylating DNA or RNA. It has the 4,5’8-trimethyl psoralen (TMP) group that can intercalate into double-stranded DNA or RNA and form covalent bonds with thymine and other pyrimidine bases when exposed to UV light (around 350 nm). Psoralen-PEG3-Biotin contains a polyethylene glycol (PEG) spacer arm (~45 Armstrong) that enhances the solubility and accessibility of the biotin moiety. Psoralen-A17-Biotin can be used for selective labeling of cell surface proteins, tissues and other biological samples. It can also be used to study the interactions between nucleic acids and proteins. Compared to the psoralen-PEG3-biotin, Psoralen-A17-Biotin is much more effective under the same conditions. It is a superior replacement for psoralen-PEG3-biotin.

Protocol

SDS

COA

Catalog	Size	Price	Quantity
39052	1 mg	Price
39053	5 mg	Price

References

View all 39 references: Citation Explorer

Hidden threat lurking in extensive hand hygiene during the Covid-19 pandemic: investigation of sensitizing molecules in gel products by hyphenated chromatography techniques.

Authors:

Salerno, Tania M G and Trovato, Emanuela and Cafeo, Giovanna and Vento, Federica and Zoccali, Mariosimone and Donato, Paola and Dugo, Paola and Mondello, Luigi

Journal:

Analytical and bioanalytical chemistry (2023): 3327-3340

Determination of Oxygen Heterocyclic Compounds in Foods Using Supercritical Fluid Chromatography-Tandem Mass Spectrometry.

Authors:

Cafeo, Giovanna and Satira, Antonella and Russo, Marina and Mondello, Monica and Dugo, Paola

Journal:

Foods (Basel, Switzerland) (2023)

Comparison of the Efficacy and Safety of Bexarotene and Photo(Chemo)Therapy Combination Therapy and Bexarotene Monotherapy for Cutaneous T-Cell Lymphoma.

Authors:

Morita, Akimichi and Tateishi, Chiharu and Ikumi, Kyoko and Hayashi, Daisuke and Nakada, Aya and Nishihara, Haruna and Torii, Kan and Nishida, Emi and Tsuruta, Daisuke

Journal:

Dermatology and therapy (2022): 615-629

Force-Dependent Intercalative Bulky DNA Adduct Formation Detected by Single-Molecule Stretching.

Authors:

Liu, Yajun and Pei, Yufeng and Xu, Jingjing and Cheng, Yuanlei and Tong, Qingyi and You, Huijuan

Journal:

Analytical chemistry (2022): 13623-13630

[Alopecia areata with good response to tofacitinib].

Authors:

Maksimow, A and Stintzing, D and Wohlrab, J

Journal:

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete (2021): 525-527

Physical properties

Molecular weight	739.89
Solvent	DMSO

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C)
UNSPSC	12171501

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Page updated on October 15, 2025