Anti-17-alpha-hydroxyprogesterone antibody *Mouse anti-human, monoclonal IgG1*

Anti-17-alpha-hydroxyprogesterone antibody

Mouse anti-human, monoclonal IgG1

17 alpha-hydroxyprogesterone (17 α-OHP) is a steroid hormone synthesized from progesterone. It acts as an agonist of the progesterone receptor and is a precursor in the biosynthesis of many other steroids such as glucocorticoids, androgens and estrogens. In clinical biology, measuring 17 α-OHP levels in the blood are useful in the detection and evaluation of congenital adrenal hyperplasia (CAH). Patients with CAH express insufficient amounts of the enzyme 21-hydroxylase, which is necessary for the conversion of 17 α-OHP into cortisol. As a result, 17 α-OHP levels in the blood build up. Anti-17 α-OHP monoclonal antibodies are highly sensitive for the detection of 17 α-OHP. They can be used for a broad range of immunoassays such as competitive chemiluminescence immunoassays (CLIA) and ELISA.

<p>Clinical comparison of AAT Bioquest’s 17 α -OHP immunoassay and a competitor’s immunoassay: 27 clinical blood samples were tested using 17 α -OHP monoclonal antibodies from AAT Bioquest on a CLIA platform. Data from this study were compared to that of a competitor’s diagnostic kit.</p>

Protocol

COA

Catalog	Size	Price	Quantity
V100195	50 ug	Price
V100196	1 mg	Price

Conjugation

We provide custom conjugation services for this antibody (e.g. labeling of Anti-17-alpha-hydroxyprogesterone antibody *Mouse anti-human, monoclonal IgG1* with HRP). A list of available labels can be found in the table below:

Label Type	Available Labels
AF	AF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750
Proteins	HRP, Alkaline Phosphatase, Streptavidin
Tandems	APC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5
Small Molecules	Biotin
Traditional Dyes	FITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5
iFluor	350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7
mFluor	UV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780

For additional information about custom conjugations, please consult our services page

here

Antibody properties

Host	mouse
Reactivity	human
Application	CLIA

Storage, safety and handling

Intended use

Research Use Only (RUO)

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Page updated on October 12, 2025