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Anti-Beta-2-microglobulin (B2M) antibody
Mouse anti-human, monoclonal IgG1
Human beta-2-microglobulin (B2M) is an 11.6 kDa non-glycosylated protein present in a variety of bodily fluids. It is a component of Class I MHC molecules and is necessary for the proper folding, binding of antigenic peptide, and surface expression of MHC-1 molecules. In long-term hemodialysis patients, B2M can accumulate to cause serious dialysis-related amyloidosis. Additionally, elevated levels of B2M are associated with rheumatoid arthritis, viral infections, cancer and aging. Anti-B2M monoclonal antibodies are highly specific for the detection of human B2M proteins. They can be used in a broad range of immunoassays such as latex enhanced turbidimetric immunoassays (LETIA), lateral-flow immunoassays (LFIA) and ELISA.
<p>Linear calibration curve for B2M in latex-enhanced turbidimetric immunoassay (LETIA): human B2M was reacted with the anti-human B2M antibody-coated latex, resulting in agglutination and an increase in turbidity. Turbidity changes were monitored using a spectrometer to quantitatively measure the B2M concentration in the sample.</p>
<p>Linear calibration curve for B2M in latex-enhanced turbidimetric immunoassay (LETIA): human B2M was reacted with the anti-human B2M antibody-coated latex, resulting in agglutination and an increase in turbidity. Turbidity changes were monitored using a spectrometer to quantitatively measure the B2M concentration in the sample.</p>
CatalogSize
Price
Quantity
V10001050 ug
Price
V1000111 mg
Price
 
Physical properties

SolventWater
Antibody properties

Hostmouse
Reactivityhuman
ApplicationELISA; LFIIA
Storage, safety and handling

Intended useResearch Use Only (RUO)
StorageFreeze (< -15 °C)
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Page updated on October 12, 2025