Anti-Beta-2-microglobulin (B2M) antibody *Mouse anti-human, monoclonal IgG2b*

Anti-Beta-2-microglobulin (B2M) antibody

Mouse anti-human, monoclonal IgG2b

Human beta-2-microglobulin (B2M) is an 11.6 kDa non-glycosylated protein present in a variety of bodily fluids. It is a component of Class I MHC molecules and is necessary for the proper folding, binding of antigenic peptide, and surface expression of MHC-1 molecules. In long-term hemodialysis patients, B2M can accumulate to cause serious dialysis-related amyloidosis. Additionally, elevated levels of B2M are associated with rheumatoid arthritis, viral infections, cancer and aging. Anti-B2M monoclonal antibodies are highly specific for the detection of human B2M proteins. They can be used in a broad range of immunoassays such as latex enhanced turbidimetric immunoassays (LETIA), lateral-flow immunoassays (LFIA) and ELISA.

<p>Clinical comparison of AAT Bioquest’s B2M reagent and commercial LETIA kit: a B2M lateral-flow immunoassay (LFIA) using anti-B2M antibody (Cat# V100015; labeled with gold) and capture antibody was compared with a commercial B2M LETIA kit. Each assay was performed using 6 blood samples which were diluted by 50-fold.</p>

Protocol

COA

Catalog	Size	Price	Quantity
V100015	50 ug	Price
V100016	1 mg	Price

Conjugation

We provide custom conjugation services for this antibody (e.g. labeling of Anti-Beta-2-microglobulin (B2M) antibody *Mouse anti-human, monoclonal IgG2b* with HRP). A list of available labels can be found in the table below:

Label Type	Available Labels
AF	AF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750
Proteins	HRP, Alkaline Phosphatase, Streptavidin
Tandems	APC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5
Small Molecules	Biotin
Traditional Dyes	FITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5
iFluor	350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7
mFluor	UV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780

For additional information about custom conjugations, please consult our services page

here

Physical properties

Solvent

Water

Antibody properties

Host	mouse
Reactivity	human
Application	LFIA; LETIA

Storage, safety and handling

Intended use	Research Use Only (RUO)
Storage	Freeze (< -15 °C)

Telephone
Fax
Email	sales@aatbio.com
International	See distributors
Bulk request	Inquire
Custom size	Inquire
Technical Support	Contact us
Request quotation	Request
Purchase order	Send to sales@aatbio.com
Shipping	Standard overnight for United States, inquire for international

Page updated on October 11, 2025