Anti-Cystatin-C protein antibody *Mouse anti-human, monoclonal IgG1*

Anti-Cystatin-C protein antibody

Mouse anti-human, monoclonal IgG1

Cystatin C (CYSC) is a non-glycosylated, low molecular weight protein synthesized by most nucleated cells. It is present in all tissues and body fluids acting as a potent inhibitor of lysosomal proteinases and as an extracellular inhibitor of cysteine proteases. CYSC is primarily used a biomarker of renal function, but also has associations with obesity, insulin resistance, hypertension, and cardiovascular mortality. Under normal conditions, CYSC in serum is 0.47 “ 1.09 mg/L. When renal function is impaired, CYCS concentration in blood will change with glomerular filtration rate (GFR). During renal failure, GFR decreases while CYSC blood concentration increases more than 10-fold. Anti-CYSC monoclonal antibodies are highly sensitive for the detection of human CYSC proteins. They can be used for a broad range of CYSC immunoassays such as latex enhanced turbidimetric immunoassays (LETIA).

<p>Clinical comparison of AAT Bioquest’s CYSC reagent and commercial kit.</p>

Protocol

COA

Catalog	Size	Price	Quantity
V100030	50 ug	Price
V100031	1 mg	Price

Conjugation

We provide custom conjugation services for this antibody (e.g. labeling of Anti-Cystatin-C protein antibody *Mouse anti-human, monoclonal IgG1* with HRP). A list of available labels can be found in the table below:

Label Type	Available Labels
AF	AF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750
Proteins	HRP, Alkaline Phosphatase, Streptavidin
Tandems	APC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5
Small Molecules	Biotin
Traditional Dyes	FITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5
iFluor	350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7
mFluor	UV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780

For additional information about custom conjugations, please consult our services page

here

Physical properties

Solvent

Water

Antibody properties

Host	mouse
Reactivity	human
Application	LETIA

Storage, safety and handling

Intended use	Research Use Only (RUO)
Storage	Freeze (< -15 °C)

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Fax
Email	sales@aatbio.com
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Purchase order	Send to sales@aatbio.com
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Page updated on October 10, 2025